Home Methylglyoxal-lowering agents as a treatment for Alzheimer's disease?: Identification of methylglyoxal-lowering agents for the treatment of advanced glycation end products-related diseases ISBN-10 9783844316186, ISBN-13 978-3844316

Methylglyoxal-lowering agents as a treatment for Alzheimer's disease?: Identification of methylglyoxal-lowering agents for the treatment of advanced glycation end products-related diseases

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Paperback: 84 pages
Publisher: LAP LAMBERT Academic Publishing (March 14, 2011)
Language: English
ISBN-10: 9783844316186
ISBN-13: 978-3844316186
ASIN: 3844316183
Product Dimensions: 5.9 x 0.2 x 8.7 inches
Format: PDF ePub TXT book

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Advanced glycation end products (AGEs) play a major role in age-related diseases like Alzheimer's disease. 1,2-dicarbonyl compounds, such as glyoxal (GO) and methylglyoxal (MGO), are involved in the formation of these AGEs. Thus, it was hypothesised that the progression of Alzheimer's disease can be slowed down by lowering the concentration of 1,2-dicarbonyl compounds, which will consequently lead to a decrease in AGE formation. Therefore, the ai...

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